Prof. Wei-Ping Liao, Director of the ION-GZMU
 
 

Prof. Weiping Liao
  • "Ambassador of Epilepsy" awarded by IBE and ILAE
  • The Associate Editor of SEIZURE-European Journal of Epilepsy
  • Vice President of China Association Against Epilepsy
  • Director of Institute of Neuroscience, GZMU & Key Laboratory of Neurogenetics and Channelopathies of the Ministry of Education of China

  Dr. Wei-Ping Liao is a Professor of Neurology at the Second Affiliated Hospital of Guangzhou Medical University in China. He is now a vice president of China Association Against Epilepsy (CAAE). He graduated from Hunan Medical University in 1983 and subsequently trained in Neurology until 1986. He obtained further training in Epileptology in the National Epilepsy Center of Japan between 1988-1989. Now, he directs the Institute of Neurosciences and Epilepsy Unit, which provides a range of services for people with neurological disorders and epilepsies. He is also the director of the Key Laboratory of Neurogenetics and Channelopathies of the Ministry of Education of China, leads a team in basic studies on epilepsy. His research interests include genetics, surgical management and pathological basis of epilepsy. He has published many papers in recent years, in journals like  Brain,Genetics in Medicine,Briefings in Bioinformatics, Neurology,Frontiers In Molecular Neuroscience,etc. He is the associate editor of SEIZURE-European Journal of Epilepsy, He also served as an editorial board member of Epilepsia, and reviewer for many journals. He is an active member of the Asian Epilepsy Academy (ASEPA). He has organized and participated in several epilepsy conferences and teaching courses in China, under the auspices of ASEPA and CAAE in recent years. He was awarded Ambassador for Epilepsy in 2011 for his contributions in this field.

EDUCATION:

  • M.D. and M.S., Hunan Medical University, Changsha, P.R. China, 1978-1986
  • Ph.D., Sun Yat-Sen University of Medical Sciences, Guangzhou, P. R. China, 1994-1997

EXPERIENCE:

  • 1991-present Institute of Neurosciences, Guangzhou Medical University, Professor (Associate Professor before 1997)
  • 1989-1991 Department of Neurology, the 1st Affiliated Hospital of Hunan Medical University, Visiting Doctor
  • 1988-1989 National Epilepsy Center of Japan, Visiting Scholar, studied under Dr. M Seino, the former vice president of International League Against Epilepsy
  • 1986-1988 Department of Neurology, the 1st Affiliated Hospital of Hunan Medical University, Resident Doctor

AWARDS:

  • The Second Prize for Scientific Research awarded by the Ministry of Education of China, 2023 
  • Ambassador for Epilepsy awarded by ILAE and IBE, 2012
  • The Second Prize for Scientific Research awarded by Scientific and Technologic Committee of Guangdong Province, 2010
  • The Second Prize for Scientific Research awarded by the Ministry of Education of China, 2003
  • The Second Prize for Scientific Research awarded by Scientific and Technologic Committee of Guangdong Province, 1995
  • Sackler Award for Chinese Doctor of the Year (1994) awarded by Sackler Foundation (US) and the Ministry of Health of China (organized by China Medical Tribune)
  • Gowers’ Prize awarded by British Branch of International League Against Epilepsy, 1990

SCIENTIFIC CAREER:

  • Engaged in epileptology since 1988, begun with the strict training in national epilepsy center of Japan, following Dr. M Seino, the former vice president of International League Against Epilepsy and the father of Asian epileptology.
  • Have done a lot of studies after being back in China, and contributed greatly to the development of epileptology in China. Elected as a vice president of China Association Against Epilepsy when it is founded in 2005.
  • Being nominated and accredited as the vice director and then director of the Institute of Neuroscience of Guangzhou Medical University since 1998 by Dr Nanshan Zhong.
  • Engaged in genetics of epilepsy and channelopathies in recent years, a lot of important works have been published since then. Headed this institute to become the Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China in 2008.

PUBLICATIONS

  1. Wang J#, Qiao JD#, Liu XR, Liu DT, Chen YH, Wu Y, Sun Y, Yu J, Ren RN, Mei Z, Liu YX, Shi YW, Jiang M, Lin SM, He N, Li B, Bian WJ, Li BM, Yi YH, Su T, Liu HK, Gu WY, Liao WP*. UNC13B variants associated with partial epilepsy with favourable outcome. Brain. 2021 Nov 29;144(10):3050-3060.2022 Apr 18;145(2):e5. PMID: 33876820; PMCID: PMC8634081.Pubmed-link

  2. Qiao JD, Li X, Li J, Guo QH, Tang XQ, Chen LZ, Su T, Yi YH, Wang J, Liao WP*. Reply: UNC13B and focal epilepsy. Brain. 2022 Apr 29;145(3):e13-e16.PMID: 35380625.Pubmed-link

  3. Shi YW#, Zhang Q#, Cai K#, Poliquin S, Shen W, Winters N, Yi YH, Wang J, Hu N, Macdonald RL, Liao WP*, Kang JQ*. Synaptic clustering differences due to different GABRB3 mutations cause variable epilepsy syndromes.Brain. 2019 Oct 1;142(10):3028-3044.PMID: 31435640; PMCID: PMC6776116.Pubmed-link

  4.  Bayat A*, Liu Z#, Luo S#, Fenger CD, H?jte AF, Isidor B, Cogne B, Larson A, Zanus C, Faletra F, Keren B, Musante L, Gourfinkel-An I, Perrine C, Demily C, Lesca G,Liao WP*, Ren D. A new neurodevelopmental disorder linked to heterozygous variants in UNC79.Genet Med Genet Med. 2023 Sep;25(9):100894.Epub 2023 May 11. PMID: 37183800.Pubmed-link

  5.  He N#, Lin ZJ#, Wang J, Wei F, Meng H, Liu XR, Chen Q, Su T, Shi YW, Yi YH, Liao WP*. Evaluating the pathogenic potential of genes with de novo variants in epileptic encephalopathies. Genet Med. 2019 Jan;21(1):17-27. Epub 2018 Jun 12. PMID: 29895856; PMCID: PMC6752304.Pubmed-link

  6.  Tang B#, Li B#, Gao LD, He N, Liu XR, Long YS, Zeng Y, Yi YH, Su T, Liao WP*. Optimization of in silico tools for predicting genetic variants: individualizing for genes with molecular sub-regional stratification. Brief Bioinform. 2020 Sep 25;21(5):1776-1786.PMID: 31686106.Pubmed-link

  7.  Mullan KA, Anderson A, Shi YW, Ding JH, Ng CC, Chen Z, Baum L, Cherny S, Petrovski S, Sham PC, Lim KS, Liao WP*, Kwan P*. Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications.Epilepsia. 2022 Apr;63(4):936-949.Epub 2022 Feb 16. PMID: 35170024; PMCID: PMC9541367.Pubmed-link

  8.  Shi YW#, Min FL#, Zhou D, Qin B, Wang J, Hu FY, Cheung YK, Zhou JH, Hu XS, Zhou JQ, Zhou LM, Zheng ZZ, Pan J, He N, Liu ZS, Hou YQ, Lim KS, Ou YM, Hui-Ping Khor A, Ng CC, Mao BJ, Liu XR, Li BM, Kuan YY, Yi YH, He XL, Deng XY, Su T, Kwan P*, Liao WP*. HLA-A*24:02 as a common risk factor for antiepileptic drug-induced cutaneous adverse reactions. Neurology.2017 Jun 6;88(23):2183-2191.Epub 2017 May 5. PMID: 28476759; PMCID: PMC5467955.Pubmed-link

  9.  Liao WP*, Shi YW, Min FL. HLA-B*1502 screening and toxic effects of carbamazepine.N Engl J Med.2011 Aug 18;365(7):672-3; author reply 673.PMID: 21848471.Pubmed-link

  10.  He N#, Li B#, Lin ZJ, Zhou P, Su T, Liao WP*. Common genetic epilepsies, pathogenicity of genes/variants, and genetic dependence.Seizure. 2023 Jul;109:38-39.Epub 2023 May 11. PMID: 37207537.Pubmed-link

  11.  Liao WP*, Chen Q, Jiang YW, Luo S, Liu XR. Editorial: Sub-molecular mechanism of genetic epilepsy.Front Mol Neurosci. 2022 Jul 26;15:958747.PMID: 35959103; PMCID: PMC9360914.Pubmed-link

  12.  Tian MQ#, Liu XR#, Lin SM#, Wang J, Luo S, Gao LD, Chen XB, Liang XY, Liu ZG, He N, Yi YH, Liao WP*; China Epilepsy Gene 1.0 Project. Variants in BRWD3 associated with X-linked partial epilepsy without intellectual disability.CNS Neurosci Ther. 2023 Feb;29(2):727-735.Epub 2022 Dec 13. PMID: 36514184; PMCID: PMC9873514.Pubmed-link

  13.  He N#, Guan BZ#, Wang J, Liu HK, Mao Y, Liu ZG, Yin F, Peng J, Xiao B, Tang BS, Zhou D, Huang G, Dai QL, Zeng Y, Han H, Zhai QX, Li B, Tang B, Li WB, Song W, Liu L, Shi YW, Li BM, Su T, Zhou P, Liu XR, Guo LW, Yi YH, Liao WP*. HCFC1 variants in the proteolysis domain are associated with X-linked idiopathic partial epilepsy: Exploring the underlying mechanism. Clin Transl Med. 2023 Jun;13(6):e1289.PMID: 37264743; PMCID: PMC10235798.Pubmed-link

  14.  Ye T#, Zhang J#, Wang J, Lan S, Zeng T, Wang H, He X, Li BM, Deng W, Liao WP*, Liu XR*. Variants in BSN gene associated with epilepsy with favourable outcome. Med Genet. 2023 Aug;60(8):776-783.Epub 2022 Dec 12. PMID: 36600631; PMCID: PMC10439262.Pubmed-link

  15.  Luo J#, Li Y#, Lv Y, Li X, Qin B, Cheng C, Liu X, Liao WP, Wang J*, Gao Z*, MPDZ variants associated with epilepsies and/or febrile seizures and the individualized genotype-phenotype correlation, Genes & Diseases,2023;11(3):101032.PMID:38292201; PMCID:PMC10825275.Pubmed-link

  16.  Zhang MW#, Liang XY#, Wang J#, Gao LD, Liao HJ, He YH, Yi YH, He N*, Liao WP*; China Epilepsy Gene 1.0 Project. Epilepsy-associated genes: an update.Seizure. 2023 Sep 23:S1059-1311(23)00254-6.Epub ahead of print.PMID: 37777370.Pubmed-link

  17.  Wu WC#, Liang XY#, Zhang DM, Jin L, Liu ZG, Zeng XL, Zhai QX, Liao WP, He N*, Meng XH*. DYNC1H1 variants associated with infant-onset epilepsy without neurodevelopmental disorders. Seizure. 2023 Oct 27:S1059-1311(23)00276-5.Epub ahead of print. PMID: 37903666.Pubmed-link

  18.  Li J#, Lin SM#, Qiao JD, Liu XR, Wang J, Jiang M, Zhang J, Zhong M, Chen XQ, Zhu J, He N, Su T, Shi YW, Yi YH, Liao WP*; China Epilepsy Gene 1.0 Project. CELSR3 variants are associated with febrile seizures and epilepsy with antecedent febrile seizures.CNS Neurosci Ther. 2022 Mar;28(3):382-389.Epub 2021 Dec 23. PMID: 34951123; PMCID: PMC8841303.Pubmed-link

  19. Zheng Chen, Sheng Luo, Zhi-Gang Liu, Yan-Chun Deng, Su-Li He, Xiao-Rong Liu, Yong-Hong Yi, Jie Wang, Liang-Di Gao, Bing-Mei Li, Zhi-Jun Wu, Zi-Long Ye, De-Hai Liang, Wen-Jun Bian, Wei-Ping Liao*, For the China Epilepsy Gene 1.0 Project.CELSR1 variants are associated with partial epilepsy of childhood.American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.2022 Oct;189B: 247– 256.PMID: 36453712.Pubmed-link

  20. Luo S#, Liu ZG#, Wang J, Luo JX, Ye XG, Li X, Zhai QX, Liu XR, Wang J, Gao LD, Liu FL, Ye ZL, Li H, Gao ZF, Guo QH, Li BM, Yi YH, Liao WP*. Recessive LAMA5 Variants Associated With Partial Epilepsy and Spasms in Infancy. Front Mol Neurosci. 2022 May 19;15:825390.PMID: 35663266.Pubmed-link

  21.  Su T#, Chen ML#, Liu LH, Meng H, Tang B, Liu XR, Liao WP*. Critical Role of E1623 Residue in S3-S4 Loop of Nav1.1 Channel and Correlation Between Nature of Substitution and Functional Alteration. Front Mol Neurosci. 2022 Jan 10;14:797628.PMID: 35082603; PMCID: PMC8785683.Pubmed-link

  22.  Tian Y#, Zhai QX#, Li XJ#, Shi Z, Cheng CF, Fan CX, Tang B, Zhang Y, He YY, Li WB, Luo S, Hou C, Chen WX*, Liao WP, Wang J*. ATP6V0C Is Associated With Febrile Seizures and Epilepsy With Febrile Seizures Plus. Front Mol Neurosci. 2022 May 6;15:889534.PMID: 35600075; PMCID: PMC9120599.Pubmed-link

  23.  Wang JY#, Wang J#, Lu XG, Song W, Luo S, Zou DF, Hua LD, Peng Q, Tian Y, Gao LD, Liao WP, He N*. Recessive PKD1 Mutations Are Associated With Febrile Seizures and Epilepsy With Antecedent Febrile Seizures and the Genotype-Phenotype Correlation.Front Mol Neurosci. 2022 May 10;15:861159.PMID: 35620448; PMCID: PMC9128595.Pubmed-link

  24.  Ma MG#, Liu XR#, Wu Y, Wang J, Li BM, Shi YW, Su T, Li B, Liu DT, Yi YH*, Liao WP*. RYR2 Mutations Are Associated With Benign Epilepsy of Childhood With Centrotemporal Spikes With or Without Arrhythmia. Front Mol Neurosci. 2021 Apr 7;15:629610.PMID: 33897349; PMCID: PMC8058200.Pubmed-link

  25.  Liu XR#, Xu XX#, Lin SM, Fan CY, Ye TT, Tang B, Shi YW, Su T, Li BM, Yi YH, Luo JH*, Liao WP*. GRIN2A Variants Associated With Idiopathic Generalized Epilepsies. Front Mol Neurosci. 2021 Oct 14;14:720984.PMID: 34720871; PMCID: PMC8551482.Pubmed-link

  26. Ye XG#, Liu ZG#, Wang J, Dai JM, Qiao PX, Gao PM, Liao WP*. YWHAG Mutations Cause Childhood Myoclonic Epilepsy and Febrile Seizures: Molecular Sub-regional Effect and Mechanism. Front Genet. 2021 Mar 9;12:632466.PMID: 33767733; PMCID: PMC7985244.Pubmed-link

  27.   Liu XR, Bian WJ, Wang J, Ye TT, Li BM, Liu DT, Tang B, Deng WW, Shi YW, Su T, Yi YH, Liao WP*. Heterozygous PGM3 Variants Are Associated With Idiopathic Focal Epilepsy With Incomplete Penetrance. Front Genet. 2020 Oct 15;11:559080.PMID: 33193641; PMCID: PMC7597759.Pubmed-link

  28. Wei F, Yan L-M, Su T, Na H, Lin Z-J, Wang J, Shi Y-W, Yi Y-H, Liao W-P*. Ion Channel Genes and Epilepsy: Functional Alteration, Pathogenic Potential, and Mechanism of Epilepsy. Neuroscience Bulletin.2017 Aug;33(4):455-477.PMID: 28488083; PMCID: PMC5567559.Pubmed-link

  29. Wang J, Lin ZJ, Liu L, Xu HQ, Shi YW, Yi YH, He N, Liao WP*. Epilepsy-associated genes. Seizure. 2017 Jan;44:11-20.PMID: 28007376.Pubmed-link

  30. Xiao-Rong Liu, Dan Huang, Jie Wang, Yi-Fan Wang, Hui Sun, Bin Tang, Wen Li, Jin-Xing Lai, Na He, Mei Wu, Tao Su, Heng Meng, Yi-Wu Shi, Bing-Mei Li, Bei-Sha Tang, Wei-Ping Liao*.Paroxysmal hypnogenic dyskinesia is associated with mutations in the PRRT2 gene. Neurol Genet. 2016 Apr; 2(2): e66.PMID: 27123484; PMCID:PMC4830198.Pubmed-link

  31. Gao QW, Hua LD, Wang J, Fan CX, Deng WY, Li B, Bian WJ, Shao CX, He N, Zhou P, Liao WP*, Shi YW*. A Point Mutation in SCN1A 5' Genomic Region Decreases the Promoter Activity and Is Associated with Mild Epilepsy and Seizure Aggravation Induced by Antiepileptic Drug.Mol Neurobiol. 2017 May;54(4):2428-2434.PMID:26969601.Pubmed-link

  32. Meng H, Xu HQ, Yu L, Lin GW, He N, Su T, Shi YW, Li B, Wang J, Liu XR, Tang B, Long YS, Yi YH, Liao WP*. The SCN1A mutation database: updating information and analysis of the relationships among genotype, functional alteration, and phenotype.Hum Mutat. 2015 Jun;36(6):573-80.PMID: 25754450.Pubmed-link

  33. Chen YJ, Shi YW, Xu HQ,Chen ML, Gao MM,Sun WW, Tang B, Zeng Y, Liao WP*. Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A. Molecular Neurobiology 2014 2015 Jun;51(3):1263-70.PMID: 24990319.Pubmed-link

  34. Zeng T1, Dong ZF, Liu SJ, Wan RP, Tang LJ, Liu T, Zhao QH, Shi YW, Yi YH, Liao WP, Long YS.A novel variant in the 3' UTR of human SCN1A gene from a patient with Dravet syndrome decreases mRNA stability mediated by GAPDH's binding.Hum Genet.2014 Jun;133(6):801-11.PMID: 24464349.Pubmed-link

  35. Dong ZF, Tang LJ, Deng GF, Zeng T, Liu SJ, Wan RP, Liu T, Zhao QH, Yi YH, Liao WP, Long YS.Transcription of the Human Sodium Channel SCN1A Gene Is Repressed by a Scaffolding Protein RACK1.Mol Neurobiol.2014 Oct;50(2):438-48.PMID: 24436055.Pubmed-link

  36. Liu T, Wan RP, Tang LJ, Liu SJ, Li HJ, Zhao QH, Liao WP, Sun XF, Yi YH, Long YS. A MicroRNA Profile in Fmr1 Knockout Mice Reveals MicroRNA Expression Alterations with Possible Roles in Fragile X Syndrome.Mol Neurobiol. 2015;51(3):1053-63.PMID: 24906954.Pubmed-link

  37. Wang JL, Mao X, Hu ZM, Li JD, Li N, Guo JF, Jiang H, Shen L, Li J, Shi YT, Xia K, Liu JY, Liao WP, Tang BS. Mutation analysis of PRRT2 in two Chinese BFIS families and nomenclature of PRRT2 related paroxysmal diseases. Neurosci Lett. 2013 Sep 27;552:40-5.PMID: 23896529.Pubmed-link

  38. Liu XR, Wu M, He N, Meng H, Wen L, Wang JL, Zhang MP, Li WB, Mao X, Qin JM, Li BM, Tang B, Deng YH, Shi YW, Su T, Yi YH, Tang BS, Liao WP*. Novel PRRT2 mutations in paroxysmal dyskinesia patients with variant inheritance and phenotypes.Genes Brain Behav.2013 Mar;12(2):234-40.PMID: 23190448.Pubmed-link

  39. Lv YD, Min FL, Liao WP, He N, Zeng T, Ma DH, Shi YW. The association between oxcarbazepine-induced maculopapular eruption and HLA-B alleles in a northern Han Chinese population. BMC Neurol. 2013; 13: 75. PMID: 23829937.Pubmed-link

  40. Deng GF, Liu SJ, Sun XS, Sun WW, Zhao QH, Liao WP, Yi YH, Long YS. A conserved region in the 3' untranslated region of the human LIMK1 gene is critical for proper expression of LIMK1 at the post-transcriptional level. Neurosci Bull. 2013;29(3):348-54.PMID:23700283.Pubmed-link

  41. He N, Min FL, Shi YW, Guo J, Liu XR, Li BM, Zhou JH, Ou YM, Liao JX, Liao WP*. Cutaneous reactions induced by oxcarbazepine in Southern Han Chinese: incidence, features, risk factors and relation to HLA-B alleles. Seizure 2012 Oct; 21(8):614-8.PMID:22818943. Pubmed-link

  42. Shi YW, Min FL, Qin B, Zou X, Liu XR, Gao MM, Wang Q, Zhou JQ, Liao WP*.Association between HLA and Stevens-Johnson Syndrome Induced by Carbamazepine in Southern Han Chinese: Genetic Markers besides B*1502? Basic Clin Pharmacol Toxicol. 2012 Jul;111(1):58-64.Epub 2012 Mar 17. PMID: 22348435.Pubmed-link

  43. Shi YW, Yu MJ, Long YS, Qin B, He N, Meng H, Liu XR, Deng WY, Gao MM, Yi YH, Li BM, Liao WP*. Mosaic SCN1A mutations in familial partial epilepsy with antecedent febrile seizures. Genes Brain Behav. 2012 Mar;11(2):170-6. PMID: 22151702.Pubmed-link

  44. Li BM, Liu XR, Yi YH, Deng YH, Su T, Zou X, Liao WP*.Autism in Dravet syndrome: prevalence, features, and relationship to the clinical characteristics of epilepsy and mental retardation.Epilepsy Behav2011 Jul;21(3):291-5.PMID: 21620773.Pubmed-link

  45. Long YS, Qin JM, Su T, Zhao QH, Yi YH, Liao WP.Human transcription factor genes involved in neuronal development tend to have high GC content and CpG elements in the proximal promoter region.J Genet Genomics 2011 Apr 20;38(4):157-63.PMID:21530899.Pubmed-link

  46. Shi YW, Min FL, Liu XR, Zan LX, Gao MM, Yu MJ, Liao WP*.Hla-B alleles and lamotrigine-induced cutaneous adverse drug reactions in the Han Chinese population.Basic Clin Pharmacol Toxicol 2011 Jul;109(1):42-6.PMID: 21306565.Pubmed-link

  47. Su T, Paradiso B, Long YS, Liao WP, Simonato M.Evaluation of cell damage in organotypic hippocampal slice culture from adult mouse: a potential model system to study neuroprotection.Brain Res 2011 Apr 18;1385:68-76.PMID: 21303673.Pubmed-link

  48. Deng GF, Qin JM, Sun XS, Kuang ZY, Su T, Zhao QH, Shi YW, Liu XR, Yu MJ, Yi YH, Liao WP, Long YS. Promoter analysis of mouse Scn3a gene and regulation of the promoter activity by GC box and CpG methylation.J Mol Neurosci2011 Jun;44(2):115-21.PMID: 21271300.Pubmed-link

  49. Min FL, Shi YW, Liu XR, Liao WP.HLA-B*1502 genotyping in two Chinese patients with phenytoin-induced Stevens-Johnson syndrome.Epilepsy Behav2011 Feb;20(2):390-1. doi: 10.1016/j.yebeh.2010.11.022. Epub 2011 Jan 7. PMID: 21216202.Pubmed-link

  50. Long YS, Deng GF, Sun XS, Yi YH, Su T, Zhao QH, Liao WP*.Identification of the transcriptional promoters in the proximal regions of human microRNA genesMol Biol Rep2011 Aug;38(6):4153-7. PMID: 21107707.Pubmed-link

  51. Long YS, Huang MQ, Liao WP.Identification of novel cyclic nucleotide phosphodiesterase gene cDNAs in the brain of guinea pig.Neurosci Bull. 2010 Oct;26(5):365-70. doi: 10.1007/s12264-010-0517-z. PMID: 20882062; PMCID: PMC5560350.Pubmed-link

  52. Wang YL, Zeng ZY, Song XW, Hao ZF, Shi YW, Tang B, Chen SQ, Gao MM, Di W, Long YS, Yi YH, Liao WP.A novel CLN2/TPP1 mutation in a Chinese patient with late infantile neuronal ceroid lipofuscinosis.Neurogenetics2011 Feb;12(1):93-5.PMID: 20820830.Pubmed-link

  53. Yu MJ, Shi YW, Gao MM, Deng WY, Liu XR, Chen L, Long YS, Yi YH, Liao WP*.Milder phenotype with SCN1A truncation mutation other than SMEI.Seizure2010 Sep;19(7):443-5.PMID:20630778.Pubmed-link

  54. Wei-Ping Liao*, Yi-Wu Shi, Yue-Sheng Long, Yang Zeng, Tian Li, Mei-Juan Yu, Tao Su, Ping Deng, Zhi-Gang Lei, Shu-Jun Xu, Wei-Yi Deng, Xiao-Rong Liu, Wei-Wen Sun, Yong-Hong Yi, Zao C. Xu ,Shumin Duan.Partial epilepsy with antecedent febrile seizures and seizure aggravation by antiepileptic drugs: associated with loss of function of Na1.1.Epilepsia 2010; 51(9):1669–1678.Link

  55. Yi YH, Sun XS, Qin JM, Zhao QH, Liao WP, Long YS*. Experimental identification of microRNA targets on the 3' untranslated region of human FMR1 gene. J Neurosci Methods.2010 Jun 30;190(1):34-8.PMID: 20435064.Pubmed-link

  56. Wei-Ping Liao. Comments on the “Revised terminology and concepts for organization of the epilepsies: Report of the Commission on Classification and Terminology”. Article in ILAE website. Article link

  57. Yue-Sheng Long, Yi-Wu Shi, Wei-Ping Liao*. Conservation-based prediction of the transcription regulatory region of SCN1A. Prog Nat Sci 2009, 19(12):1675-1681.Article link

  58. Su T, Cong WD, Long YS, Luo AH, Sun WW, Deng WY, Liao WP*. Altered expression of voltage-gated potassium channel 4.2 and voltage-gated potassium channel 4-interacting protein, and changes in intracellular calcium levels following lithium-pilocarpine-induced status epilepticus. Neuroscience. 2008 Dec 2;157(3):566-76. Pubmed-link

  59. Long YS, Zhao QH, Su T, Cai YL, Zeng Y, Shi YW, Yi YH, Chang HH, Liao WP*. Identification of the promoter region and the 5'-untranslated exons of the human voltage-gated sodium channel Nav1.1 gene (SCN1A) and enhancement of gene expression by the 5'-untranslated exons. J Neurosci Res. 2008 Nov 15;86(15):3375-81. Pubmed-link

  60. Yue-Sheng Long, Qi-Hua Zhao, Tao Zeng, Wei-Wen Sun, Wei-Ping Liao*. Characterization of The Promoter Region and Upstream Regulation Region of Human and Mouse SCN3A Gene*. Prog Biochem Biophys 2009; 36(3):339-345.  Fulltext-Link

  61. LF Qiu, TJ Lu, XL Hu, YH Yi, WP Liao, ZQ Xiong*. Limbic epileptogenesis in a mouse model of fragile X syndrome. Cereb Cortex 2008; Oct 1.  Pubmed-link

  62. Yi YH, Guo WC, Sun WW, Su T, Lin H, Chen SQ, Deng WY, Zhou W, Liao WP*. Neuroprotection of lamotrigine on hypoxic-ischemic brain damage in neonatal rats: Relations to administration time and doses. Biologics 2008; 2(2):339-44. Fulltext-Link

  63. Wei ZX, Yi YH*, Sun WW, Wang R, Su T, Bai YJ, Liao WP. Expression changes of microtubule associated protein 1B in the brain of Fmr1 knockout mice. Neurosci Bull. 2007 Jul;23(4):203-8. Pubmed-link

  64. Su T, Luo AH, Cong WD, Sun WW, Deng WY, Zhao QH, Zhang ZH, Liao WP*. Immunohistochemical investigation of voltage-gated potassium channel-interacting protein 1 in normal rat brain and Pentylenettrazole-induced seizures. Neurosci Bull. 2006 Jul;22(4):195-203. Pubmed-link

  65. Liao WP*, Chen L, Yi YH, Sun WW, Gao MM, Su T, Yang SQ. Study of antiepileptic effect of extracts from Acorus tatarinowii Schott. Epilepsia. 2005;46 Suppl 1:21-4. Pubmed-link

  66. Wei-Ping Liao*, Yi-Wu Shi, Bing Qin, Tian Li, Mei-Juan Yu, Yu-Hong Deng, Xiao-Rong Liu, Yong-Hong Yi, Lun-Jiao FU, Wi-Yi Deng, Bing-Mei Li, Tao Su, Yue-Sheng Long. Partial epilepsy with febrile seizure plus: A subtype of GEFS+ or SME? Neurology Asia 2007;12(Supplement 1):78–79.  Fulltext-link

  67. Wei-Ping Liao*. Antiepileptic drug trials with greater attention to daily clinical practice and special epilepsy syndromes.Neurology asia 2007; 12(Supplement1):30–32.  Fulltext-link

  68. Chang HH, Su T, Sun WW, Zhao QH, Qin B, Liao WP*. Changes of potassium channels Kv4.2, Kv4.3 and Kv channel interacting protein 1 in amygdala kindling epilepsy: experiment with rats. Zhonghua Yi Xue Za Zhi. 2006 Dec 19;86(47):3315-8. Pubmed-link

  69. Wei-Ping Liao*, Shao-Qing Yang, Yong-Hong Yi, et al. An open-label study of topiramate as add-on therapy for epilepsy using slow titration. Neurology Asia 2005, 10:99-104.  Fulltext-link

  70. Liao W* (invited presentation). Genetic Testing for Non-Familial Epilepsies. Abstract book of the 7th Asian & Oceanian Epilepsy Congress. Xiamen, China; 2008:15.

  71. Liao W*, Yu M, Shi Y, et al. Partial Epilepsy with Febrile Seizures Plus: A Subtype of Nav1.1 Channelopathies. Abstract book of the 7th Asian & Oceanian Epilepsy Congress. Xiamen, China; 2008:30.

  72. Yi YH, Liao WP, Lu X. Simultaneous determination of tryptophan, 5-hydroxytryptophan, 5-hydroxytryptamine, 5-hydroxyindoleacetic acid, 4-hydroxy-3-methoxyphenylacetic acid and 3-methoxy-4-hydroxyphenylglycol in human cerebrospinal fluid. J Chromatogr B Biomed Appl. 1994 Nov 4;661(1):143-8. Pubmed-link

     #,co-first authors；*, corresponding author

 

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